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Research Grants 2017


To view an abstract, select an author from the vertical list on the left.

2017 Grants - Lin

Cerebral Perfusion and Metabolism in Chronic Traumatic Encephalopathy

Alexander Peter Lin, Ph.D.
Brigham and Women’s Hospital
Boston, Massachusetts

2017 Alzheimer’s Association Research Grant (AARG)

Can brain imaging distinguish chronic traumatic encephalopathy from other forms of dementia?

Background
Chronic traumatic encephalopathy (CTE) is a progressive brain disease caused by repeated traumatic brain injury, such as repeated concussions. Many of the symptoms of CTE, such as memory problems and accumulation of the protein tau in the brain, are similar to the symptoms of Alzheimer’s disease. Because of these similarities, it is often not possible for doctors to distinguish between CTE and Alzheimer’s disease or other causes of dementia until a brain autopsy can be performed.

Research Plan
Alexander Peter Lin, Ph.D., and colleagues are working to develop ways to distinguish between CTE and other forms of dementia that can be used in medical clinics and for future research. Dr. Lin’s team plans to study a group of retired football players, who have high rates of CTE, and compare them with people who have Alzheimer’s disease and with people of the same age who have healthy brain function. The researchers will take advantage of an existing study that is already collecting images of tau in the brain, as well as information from blood and brain function tests. Dr. Lin and colleagues will collect additional information about the brain’s blood flow and brain chemistry, along with the imaging in an effort to identify patterns that are unique to CTE.

Impact
This research may lead to methods that can be used in future research or in medical clinics to identify people who have CTE, and to distinguish them from people who have Alzheimer’s disease or other dementias. That ability will allow better research in to the causes and potential treatments for each of the different brain conditions.


Alzheimer's Association International Conference | July 16-20, 2017, London, England

Abstract Submissions Now Open

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